Publications
FATP2-mediated lipid metabolism enhances chimeric antigen receptor T-cell therapy resistance in B-cell acute lymphoblastic leukemia
Clarissa Garcia, Kaylyn U. Lyons, Julian Grandvallet Contreras, Tian Liu, Alexis J. Donnelly, Amanda J. Novak, Amy Argabright, Colin Anderson, Abby Grier, Sabrina Smith, Joshua Michlin, Jesutomisin Olusoji, Railey G. Mikeska, Xin Zhou, Huimin Geng, Jeremy T. Rahkola, Hiten N. Patel, Jeffrey G. Jacot, Markus Müschen, Angelo D’Alessandro, John E. Dick, Ilaria Iacobucci, Charles G. Mullighan, Julie A. Reisz, Tzu Phang, M. Eric Kohler, and Matthew T. Witkowski.
Leukemia (2026)
Flow cytometric assessment of leukemia-associated monocytes in childhood B-cell acute lymphoblastic leukemia outcome
NUDT21 limits CD19 levels through alternative mRNA polyadenylation in
B cell acute lymphoblastic leukemia
Witkowski MT*, Lee S*, Wang E*, Lee AK, Talbot A, Ma C, Tsopoulidis N, Brumbaugh J, Zhao Y, Roberts KG, Hogg SJ, Nomikou S, Ghebrechristos YE, Thandapani P, Mullighan CG, Hochedlinger K, Chen W, Abdel-Wahab O, Eyquem J & Aifantis I.
Nature Immunology (2022)
Extensive Remodeling of the Immune Microenvironment in B-cell Acute Lymphoblastic Leukemia
Witkowski MT*, Dolgalev I*, Evensen NA, Ma C, Chambers T, Roberts CG, Sreeram S, Dai Y, Tikhonova AN, Lasry A, Qu C, Pei D, Cheng C, Robbins GA, Pierro J, Selvaraj S, Mezzano V, Daves M, Lupo PJ, Scheurer ME, Loomis CA, Mullighan CG, Chen W, Rabin KR, Tsirigos A, Carroll WL & Aifantis I.
Cancer Cell (2020)
Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome
Witkowski MT, Hu Y, Roberts KG, Boer JM, McKenzie MD, Liu GJ, Le Grice OD, Tremblay CS, Ghisi M, Willson TA, Horstmann MA, Aifantis I, Cimmino L, Frietze S, den Boer ML, Mullighan CG, Smyth GK, Dickins RA.
J Exp Med (2017)
